Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408144 | 0.77 | HDAC1 (0.62) | HDAC6HDAC1HDAC8HPGDCYP1A2 | |
| SCHEMBL2410440 | 0.76 | HDAC1 (0.47) | HDAC6HDAC1HDAC8HPGDCYP1A2 | |
| SCHEMBL2410507 | 0.76 | HDAC6 (0.44) | HDAC6HDAC1HDAC8HPGDSMAPT | |
| SCHEMBL12789158 | 0.74 | HPGD (0.69) | HDAC6HDAC1HDAC8HPGDCYP1A2 | |
| SCHEMBL14662082 | 0.73 | HPGDS (0.63) | HDAC6HDAC1HDAC8HPGDCYP1A2 | |
| SCHEMBL2470040 | 0.73 | HDAC6 (0.70) | HDAC6HDAC1HDAC8HPGDSMN1; SMN2 | |
| SCHEMBL2406942 | 0.72 | HDAC1 (0.56) | HDAC6HDAC1HDAC8RAB9AHDAC3 | |
| SCHEMBL2408211 | 0.72 | EPHX2 (0.48) | HDAC6HDAC1HDAC8SMN1; SMN2HDAC3 | |
| SCHEMBL3436271 | 0.72 | HPGD (0.66) | HDAC6HDAC1HDAC8HPGDCYP1A2 | |
| SCHEMBL12790089 | 0.72 | HPGD (0.69) | HDAC6HDAC1HDAC8HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |