Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569859 | 0.77 | HDAC6 (0.73) | HDAC6HDAC8HDAC1HDAC3HDAC11 | |
| SCHEMBL6755639 | 0.77 | ALDH1A1 (0.71) | ALDH1A1LMNAALOX12SMN1; SMN2HDAC4 | |
| SCHEMBL2410147 | 0.76 | HDAC6 (0.64) | HDAC6HDAC8HDAC1ALDH1A1 | |
| SCHEMBL2470040 | 0.76 | HDAC6 (0.70) | HDAC6HDAC8HDAC1HDAC3HDAC11 | |
| SCHEMBL2736629 | 0.76 | KMT2A (0.56) | PPARGALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2409971 | 0.76 | HDAC6 (0.67) | HDAC6HDAC8HDAC1ALDH1A1LMNA | |
| SCHEMBL8250757 | 0.75 | LMNA (0.65) | EPHX2PPARGLMNASMN1; SMN2 | |
| SCHEMBL6919015 | 0.75 | HDAC6 (0.62) | HDAC6HDAC8HDAC1HDAC3HDAC2 | |
| SCHEMBL2413536 | 0.75 | HDAC6 (0.56) | EPHX2HDAC6HDAC8HDAC1ALDH1A1 | |
| SCHEMBL296885 | 0.74 | HDAC6 (0.60) | HDAC6HDAC8HDAC1HDAC3HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |