Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SPR | P35270 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26890923 | 0.79 | SPR (0.66) | SMN1; SMN2RAB9ASPRMAPTADORA2A | |
| SCHEMBL14150893 | 0.78 | ADORA2A (0.41) | SMN1; SMN2RAB9AADORA2AADORA1TGFBR1 | |
| SCHEMBL8267253 | 0.77 | RAB9A (0.71) | SMN1; SMN2RAB9ASPRMAPTPDE5A | |
| SCHEMBL2913480 | 0.75 | NPC1 (0.64) | RAB9AMAPTHTTKDM4EALDH1A1 | |
| SCHEMBL13789323 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ASPRMAPTPDE5A | |
| SCHEMBL1369682 | 0.74 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9ASPRMAPTPDE5A | |
| SCHEMBL5396554 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ASPRMAPTPDE5A | |
| SCHEMBL24743603 | 0.72 | PARP1 (0.62) | RAB9AHTTALDH1A1L3MBTL1CCR1 | |
| SCHEMBL26158246 | 0.71 | SPR (0.67) | SMN1; SMN2RAB9ASPRMAPTPDE5A | |
| SCHEMBL960306 | 0.71 | MAPT (0.62) | SMN1; SMN2RAB9ASPRMAPTPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539338-A1 | NOVEL MICROBICIDES | Syngenta Participations AG (CH) | 2013-01-02 | — | — | EP | claimed |
| US-20120316184-A1 | NOVEL MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-13 | — | — | US | claimed |
| WO-2011104183-A1 | NOVEL MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-01 | — | — | WO | claimed |
| EP-2539338-A1 | NOVEL MICROBICIDES | Syngenta Participations AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| US-20120316184-A1 | NOVEL MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-13 | — | — | US | disclosed |
| WO-2011104183-A1 | NOVEL MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316184-A1 | NOVEL MICROBICIDES | NOX1, MSR1, FPR1 | SMN1; SMN2 3707/4885RAB9A 2527/4885SPR 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.