Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 9/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740163 | 0.77 | METAP1 (0.60) | TGFBR1ADORA2AADORA1CCR1CCR8 | |
| SCHEMBL30443483 | 0.77 | CCR1 (0.42) | TGFBR1ADORA2AADORA1CCR1CCR8 | |
| SCHEMBL2409139 | 0.75 | PDE4A (0.41) | TGFBR1ADORA2AAXLMKNK1MKNK2 | |
| SCHEMBL2913742 | 0.75 | METAP1 (0.62) | TGFBR1CCR1CCR8MAPK14METAP1 | |
| SCHEMBL14103869 | 0.75 | RAB9A (0.47) | AXLMKNK1MKNK2MAPK14POLB | |
| SCHEMBL14104139 | 0.73 | RAB9A (0.50) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL4744102 | 0.72 | PDE4A (0.56) | ADORA2AADORA1AXLMKNK1MKNK2 | |
| SCHEMBL8544228 | 0.72 | LMNA (0.56) | TGFBR1CCR1CCR8MAPK14GRM5 | |
| SCHEMBL13789329 | 0.72 | AXL (0.42) | TGFBR1ADORA2AADORA1AXLMKNK1 | |
| SCHEMBL6687454 | 0.72 | TGFBR1 (0.72) | TGFBR1ADORA2AADORA1MAPK14SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539338-A1 | NOVEL MICROBICIDES | Syngenta Participations AG (CH) | 2013-01-02 | — | — | EP | claimed |
| US-20120316184-A1 | NOVEL MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-13 | — | — | US | claimed |
| WO-2011104183-A1 | NOVEL MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-01 | — | — | WO | claimed |
| EP-2539338-A1 | NOVEL MICROBICIDES | Syngenta Participations AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| US-20120316184-A1 | NOVEL MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-13 | — | — | US | disclosed |
| WO-2011104183-A1 | NOVEL MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316184-A1 | NOVEL MICROBICIDES | NOX1, MSR1, FPR1 | TGFBR1 1674/4885ADORA2A 1826/4885ADORA1 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.