Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413912 | 0.92 | MAPK14 (0.37) | MAPK14DDR2PPARGPPARA | |
| SCHEMBL2416271 | 0.90 | MAPK14 (0.36) | MAPK14DDR2PPARGCTSBPPARA | |
| SCHEMBL2417271 | 0.89 | PPARA (0.37) | MAPK14DDR2PPARGL3MBTL1ALDH1A1 | |
| SCHEMBL2415495 | 0.88 | MAPK14 (0.36) | MAPK14DDR2L3MBTL1LMNACTSB | |
| SCHEMBL2413347 | 0.88 | PPARG (0.38) | PPARGLMNAPPARAMAPTCYP1A2 | |
| SCHEMBL2413472 | 0.88 | MAPK14 (0.36) | MAPK14DDR2PPARGL3MBTL1ALDH1A1 | |
| SCHEMBL2416901 | 0.88 | MAPK14 (0.36) | MAPK14DDR2PPARGL3MBTL1ALDH1A1 | |
| SCHEMBL2418172 | 0.87 | MAPK14 (0.39) | MAPK14DDR2PPARGL3MBTL1CTSB | |
| SCHEMBL2413999 | 0.86 | MAPK14 (0.41) | MAPK14DDR2PPARGL3MBTL1ALDH1A1 | |
| SCHEMBL2412840 | 0.85 | MAPK14 (0.36) | MAPK14DDR2PPARGL3MBTL1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026370-B2 | Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-27 | — | — | US | claimed |