Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2415495 | 0.89 | MAPK14 (0.36) | MAPK14DDR2SLC22A12L3MBTL1KDM4E | |
| SCHEMBL2416901 | 0.88 | MAPK14 (0.36) | MAPK14DDR2PPARGPPARAL3MBTL1 | |
| SCHEMBL2408602 | 0.88 | MAPK14 (0.39) | MAPK14DDR2PPARGPPARAL3MBTL1 | |
| SCHEMBL2413999 | 0.85 | MAPK14 (0.41) | MAPK14DDR2PPARGPPARAL3MBTL1 | |
| SCHEMBL2412840 | 0.84 | MAPK14 (0.36) | MAPK14DDR2PPARGPPARAL3MBTL1 | |
| SCHEMBL2413912 | 0.84 | MAPK14 (0.37) | MAPK14DDR2PPARGPPARAPPARD | |
| SCHEMBL2418172 | 0.82 | MAPK14 (0.39) | MAPK14DDR2SLC22A12PPARGPPARA | |
| SCHEMBL2416271 | 0.82 | MAPK14 (0.36) | MAPK14DDR2PPARGPPARACTSB | |
| SCHEMBL2417271 | 0.81 | PPARA (0.37) | MAPK14DDR2PPARGPPARAL3MBTL1 | |
| SCHEMBL2414890 | 0.78 | MAPK14 (0.37) | MAPK14DDR2PPARAL3MBTL1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026370-B2 | Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-27 | — | — | US | claimed |