Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412840 | 0.92 | MAPK14 (0.36) | MAPK14DDR2SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL2413472 | 0.89 | MAPK14 (0.36) | MAPK14DDR2LMNAKDM4ESLC22A12 | |
| SCHEMBL2416901 | 0.89 | MAPK14 (0.36) | MAPK14DDR2LMNASMN1; SMN2KDM4E | |
| SCHEMBL2408602 | 0.88 | MAPK14 (0.39) | MAPK14DDR2LMNAL3MBTL1CYP1A2 | |
| SCHEMBL2413999 | 0.86 | MAPK14 (0.41) | MAPK14DDR2SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL2413912 | 0.85 | MAPK14 (0.37) | MAPK14DDR2 | |
| SCHEMBL2417271 | 0.83 | PPARA (0.37) | MAPK14DDR2LMNAKDM4EL3MBTL1 | |
| SCHEMBL2418172 | 0.83 | MAPK14 (0.39) | MAPK14DDR2SLC22A12L3MBTL1CYP1A2 | |
| SCHEMBL2416271 | 0.83 | MAPK14 (0.36) | MAPK14DDR2CTSB | |
| SCHEMBL2414890 | 0.79 | MAPK14 (0.37) | MAPK14DDR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026370-B2 | Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-09-27 | — | — | US | claimed |