SCHEMBL240897

SCHEMBL240897

CC(=Cc1ccccc1-c1ccccc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.55
APEX1 P27695 8/20 0.50
LTB4R Q15722 1/20 0.49
LTB4R2 Q9NPC1 1/20 0.49
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
NR4A2 P43354 1/20 0.45
RXRG P48443 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 1/20 0.42
GRIN2D O15399 2/20 0.41
GRIN3B O60391 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2B Q13224 2/20 0.41
GRIN2C Q14957 2/20 0.41
GRIN3A Q8TCU5 2/20 0.41
BACE1 P56817 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5852799 1.00 AKR1C3 (0.55) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL7764991 0.90 AKR1C3 (0.61) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL7764986 0.90 AKR1C3 (0.61) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL22042826 0.90 APEX1 (0.49) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL244853 0.86 AKR1C3 (0.49) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL8084752 0.86 AKR1C3 (0.49) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL8746671 0.84 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL31666241 0.84 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL3893886 0.84 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL22042820 0.82 AKR1C3 (0.52) AKR1C3APEX1RXRARXRBNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070043143-A1 Active energy beam-curable composition for optical material THOMSON LICENSING (FR) 2007-02-22 US claimed
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed
EP-0407771-B1 Holographic photopolymer compositions and elements for refractive index imaging DU PONT (US) 1998-09-30 EP claimed
EP-0441383-B1 Use of a copolymer for the making of contact lenses MITSUBISHI RAYON CO (JP) 1996-05-08 EP claimed
EP-0420225-B1 PHOTOPOLYMER FILM FOR HOLOGRAPHY E.I. du Pont de Nemours and Company (US) 1993-02-24 EP claimed
CN-116997464-A Glass laminate article and adhesive composition therefor 康宁股份有限公司 2023-11-03 CN disclosed
EP-3970970-B1 RETROREFLECTIVE SHEET, USE AND PRODUCTION METHOD KIWA CHEMICAL IND CO LTD (JP) 2023-08-23 EP disclosed
EP-4224244-A1 EYEGLASS LENS Hoya Lens Thailand Ltd. (TH) 2023-08-09 EP disclosed
EP-4224245-A1 SPECTACLE LENS Hoya Lens Thailand Ltd. (TH) 2023-08-09 EP disclosed
US-20230176250-A1 SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2023-06-08 US disclosed
US-20230111587-A1 SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2023-04-13 US disclosed
US-20220155501-A1 RETROREFLECTIVE SHEET KIWA CHEMICAL INDUSTRY CO., LTD. (JP) 2022-05-19 US disclosed
WO-2005089150-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS USA INC. (US) 2005-09-29 WO disclosed
EP-1566261-A1 RETROREFLECTION SHEET Kiwa Chemical Industry Co., Ltd. (JP) 2005-08-24 EP disclosed
US-20030087163-A1 Volume type hologram recording photosensitive composition, volume type hologram recording medium using the same and method of producing volume type hologram DAI NIPPON PRINTING CO., LTD. (JP) 2003-05-08 US disclosed
US-6046791-A Polymer dispersed liquid crystal electro-optical device and method for manufacturing the same SEIKO EPSON CORPORATION (JP) 2000-04-04 US disclosed
EP-0821260-A1 POLYMER-DISPERSED LIQUID-CRYSTAL ELECTROOPTICAL DEVICE AND METHOD OF PRODUCTION THEREOF SEIKO EPSON CORPORATION (JP) 1998-01-28 EP disclosed
EP-0572077-A1 Organic glass with a high refractive index ENICHEM SYNTHESIS S.p.A. (IT) 1993-12-01 EP disclosed
EP-0363571-B1 1,2-NAPHTHOQUINONE-2-DIAZIDO-SULPHONAMIDES AND LIGHT SENSITIVE MIXTURES CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-17 EP disclosed
EP-0363571-A1 1,2-Naphthoquinone-2-diazido-sulphonamides and light sensitive mixtures containing them HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-18 EP disclosed