SCHEMBL8084752

SCHEMBL8084752

CC(=Cc1cccc(-c2ccccc2)c1-c1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.49
APEX1 P27695 8/20 0.45
LTB4R Q15722 1/20 0.43
LTB4R2 Q9NPC1 1/20 0.43
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
NR4A2 P43354 1/20 0.41
RXRG P48443 1/20 0.41
HNF4A P41235 1/20 0.41
KDM4E B2RXH2 1/20 0.38
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
BCAT2 O15382 1/20 0.36
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5852799 0.86 AKR1C3 (0.55) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL240897 0.86 AKR1C3 (0.55) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL244853 0.84 AKR1C3 (0.49) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL7764991 0.81 AKR1C3 (0.61) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL7764986 0.81 AKR1C3 (0.61) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL8746671 0.78 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL3893886 0.78 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL31666241 0.78 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL22042826 0.77 APEX1 (0.49) AKR1C3APEX1LTB4RLTB4R2RXRA
Acetic Acid SCHEMBL31401913 0.77 HNF4A (0.53) HNF4AHDAC4HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6046791-A Polymer dispersed liquid crystal electro-optical device and method for manufacturing the same SEIKO EPSON CORPORATION (JP) 2000-04-04 US disclosed
EP-0821260-A1 POLYMER-DISPERSED LIQUID-CRYSTAL ELECTROOPTICAL DEVICE AND METHOD OF PRODUCTION THEREOF SEIKO EPSON CORPORATION (JP) 1998-01-28 EP disclosed