SCHEMBL244853

SCHEMBL244853

CC(=Cc1cccc(-c2ccccc2)c1C=C(C)C(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.49
APEX1 P27695 8/20 0.45
LTB4R Q15722 1/20 0.43
LTB4R2 Q9NPC1 1/20 0.43
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
NR4A2 P43354 1/20 0.41
RXRG P48443 1/20 0.41
KDM4E B2RXH2 1/20 0.38
HNF4A P41235 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
BCAT2 O15382 1/20 0.36
PTGS2 P35354 1/20 0.35
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2303525 0.88 BCAT2 (0.41) AKR1C3APEX1LTB4RLTB4R2KDM4E
SCHEMBL5852799 0.86 AKR1C3 (0.55) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL240897 0.86 AKR1C3 (0.55) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL8746657 0.84 AKR1C3 (0.55) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL8746654 0.84 AKR1C3 (0.55) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL8084752 0.84 AKR1C3 (0.49) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL7764991 0.81 AKR1C3 (0.61) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL7764986 0.81 AKR1C3 (0.61) AKR1C3APEX1LTB4RLTB4R2RXRA
SCHEMBL8746671 0.78 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL31666241 0.78 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025127853-A1 COMPOSITE BULK BLOCK FOR DENTAL PROSTHESIS FABRICATION, MANUFACTURING METHOD THEREFOR, AND PROSTHESIS FABRICATED THEREFROM 주식회사 하스 2025-06-19 WO claimed
WO-2024248386-A1 COMPOSITE BULK BLOCK FOR MANUFACTURING PROSTHESIS, MANUFACTURING METHOD THEREFOR, AND PROSTHESIS MANUFACTURED THEREFROM 주식회사 하스 2024-12-05 WO claimed
EP-4360588-A1 BULK BLOCK FOR MANUFACTURING DENTAL PROSTHESIS Hass Co., Ltd. (KR) 2024-05-01 EP claimed
US-20240130934-A1 BULK BLOCK FOR MANUFACTURING DENTAL PROSTHESIS HASS CO., LTD. (KR) 2024-04-25 US claimed
CN-117089285-A Automobile tail lamp repairing method 李永均 2023-11-21 CN claimed
EP-4134043-A1 CUTTABLE ABUTMENT-INTEGRATED PROSTHETIC BLOCK AND METHOD FOR MANUFACTURING SAME Hass Co., Ltd. (KR) 2023-02-15 EP claimed
EP-4129232-A1 DENTAL PROSTHESIS HAVING STRUCTURE SIMILAR TO THAT OF NATURAL TEETH, AND MANUFACTURING METHOD THEREFOR Hass Co., Ltd. (KR) 2023-02-08 EP claimed
US-20230030155-A1 MACHINABLE ABUTMENT-INTEGRATED PROSTHETIC BLOCK AND METHOD FOR MANUFACTURING SAME HASS CO., LTD. (KR) 2023-02-02 US claimed
US-20230021279-A1 DENTAL PROSTHESIS HAVING STRUCTURE SIMILAR TO THAT OF NATURAL TEETH, AND MANUFACTURING METHOD THEREFOR HASS CO., LTD. (KR) 2023-01-19 US claimed
WO-2022270973-A1 BULK BLOCK FOR MANUFACTURING DENTAL PROSTHESIS 주식회사 하스 2022-12-29 WO claimed
EP-1006095-B1 Method for fabricating endodontic, orthodontic, and direct restorations having infused ceramic network UNIV BOSTON (US) 2008-05-14 EP claimed
US-6881488-B2 Method for fabricating endodontic, orthodontic, and direct restorations having infused ceramic network TRUSTEES OF BOSTON UNIVERSITY (US) 2005-04-19 US claimed
EP-0701808-B1 Infused ceramic network for fabricating odontoforms and dental restorations UNIV BOSTON (US) 2002-12-04 EP claimed
US-20020162482-A1 Method for fabricating endodontic, orthodontic, and direct restorations having infused ceramic network GIORDANO RUSSELL A (US) 2002-11-07 US claimed
US-6271282-B1 Method for fabricating endodontic orthodontic and direct restorations having infused ceramic network TRUSTEES OF BOSTON UNIVERSITY 2001-08-07 US claimed
US-6159417-A Method for fabricating ceramic network material TRUSTEES OF BOSTON UNIVERSITY (US) 2000-12-12 US claimed
EP-1006095-A2 Method for fabricating endodontic, orthodontic, and direct restorations having infused ceramic network TRUSTEES OF BOSTON UNIVERSITY (US) 2000-06-07 EP claimed
US-5843348-A Method for fabricating odontoforms and dental restorations having infused ceramic network TRUSTEES OF BOSTON UNIVERSITY (US) 1998-12-01 US claimed
US-5680185-A Polymer dispersed liquid crystal (PDLC) display apparatus SEIKO EPSON CORPORATION (JP) 1997-10-21 US claimed
EP-0701808-A2 Infused ceramic network for fabricating odontoforms and dental restorations TRUSTEES OF BOSTON UNIVERSITY (US) 1996-03-20 EP claimed