SCHEMBL24092242

SCHEMBL24092242

CSC(C)Oc1c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c2c1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLH Q9Y253 7/20 0.70
▸ KDM4E B2RXH2 4/20 0.70
▸ MEN1 O00255 4/20 0.70
▸ KMT2A Q03164 4/20 0.70
▸ POLB P06746 3/20 0.70
▸ GAA P10253 3/20 0.70
▸ RECQL P46063 3/20 0.70
▸ HSD17B10 Q99714 3/20 0.70
▸ MMP1 P03956 2/20 0.70
▸ MAPT P10636 2/20 0.70
▸ APEX1 P27695 2/20 0.70
▸ BLM P54132 2/20 0.70
▸ HTT P42858 1/20 0.70
▸ TUBB4A P04350 1/20 0.61
▸ TUBB P07437 1/20 0.61
▸ TUBA3C P0DPH7 1/20 0.61
▸ TUBA1B P68363 1/20 0.61
▸ TUBA4A P68366 1/20 0.61
▸ TUBB4B P68371 1/20 0.61
▸ TUBB3 Q13509 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041625 0.89 POLH (0.76) POLHKDM4EMEN1KMT2APOLB
SCHEMBL22549001 0.88 POLH (0.74) POLHKDM4EMEN1KMT2APOLB
3-O-Methylquercetin SCHEMBL380558 0.83 POLH (1.00) POLHKDM4EMEN1KMT2APOLB
3-O-Methylquercetin SCHEMBL29897544 0.83 POLH (1.00) POLHKDM4EMEN1KMT2APOLB
SCHEMBL14786208 0.82 POLH (0.81) POLHKDM4EMEN1KMT2APOLB
SCHEMBL15928808 0.81 POLH (0.71) POLHKDM4EMEN1KMT2APOLB
SCHEMBL17620267 0.81 POLH (0.78) POLHKDM4EMEN1KMT2APOLB
SCHEMBL28297226 0.81 POLH (0.79) POLHKDM4EMEN1KMT2APOLB
SCHEMBL17102291 0.81 POLH (0.82) POLHKDM4EMEN1KMT2APOLB
SCHEMBL10861623 0.81 POLH (0.78) POLHKDM4EMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11197878-B2 Anti-inflammatory composition including novel quercetin-based compound AMOREPACIFIC CORPORATION (KR) 2021-12-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11197878-B2 Anti-inflammatory composition including novel quercetin-based compound TEAD4, TEAD3, TEAD2 POLH 3713/4885KDM4E 2585/4885MEN1 4771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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