Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656237 | 0.90 | P2RX3 (0.42) | P2RX3 | |
| SCHEMBL20652950 | 0.87 | P2RX7 (0.35) | FFAR4P2RX7P2RX3ALOX5APFEN1 | |
| SCHEMBL20652818 | 0.86 | CNR2 (0.35) | P2RX3MDM2USP1 | |
| SCHEMBL24095552 | 0.86 | CACNA2D1 (0.34) | FFAR4P2RX3PDE10AMDM2USP1 | |
| SCHEMBL20652800 | 0.85 | ENPP2 (0.32) | P2RX3 | |
| SCHEMBL20656170 | 0.84 | P2RX3 (0.34) | P2RX3MDM2USP1 | |
| SCHEMBL20655938 | 0.83 | ACHE (0.34) | FFAR4P2RX3MDM2USP1 | |
| SCHEMBL20652824 | 0.83 | ACACB (0.32) | — | |
| SCHEMBL24095969 | 0.82 | P2RX3 (0.36) | P2RX3USP1 | |
| SCHEMBL20652951 | 0.78 | FFAR4 (0.36) | FFAR4P2RX7P2RX3ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652176-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2021-12-15 | — | — | EP | disclosed |