Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 12/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20652776 | 0.79 | P2RX3 (0.38) | P2RX3MEN1KMT2A | |
| SCHEMBL20656198 | 0.77 | P2RX3 (0.38) | P2RX3 | |
| SCHEMBL20652797 | 0.74 | HIF1A (0.46) | ALDH1A1TSHRP2RX3MEN1KMT2A | |
| SCHEMBL22105453 | 0.73 | MEN1 (0.35) | P2RX3MEN1KMT2ATGFBR1 | |
| SCHEMBL19375462 | 0.71 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL20656202 | 0.70 | CNOT7 (0.50) | P2RX3MEN1KMT2A | |
| SCHEMBL22105580 | 0.70 | LMNA (0.49) | ALDH1A1TSHRP2RX3MEN1KMT2A | |
| SCHEMBL20432337 | 0.70 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL21316331 | 0.69 | P2RX3 (0.45) | P2RX3 | |
| SCHEMBL19375035 | 0.68 | P2RX3 (0.44) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652176-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2021-12-15 | — | — | EP | disclosed |