Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 17/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20652776 | 0.87 | P2RX3 (0.38) | P2RX3 | |
| SCHEMBL20653052 | 0.82 | P2RX3 (0.35) | P2RX3 | |
| SCHEMBL20653068 | 0.80 | P2RX3 (0.43) | P2RX3 | |
| SCHEMBL20652818 | 0.79 | CNR2 (0.35) | P2RX3 | |
| SCHEMBL20656170 | 0.79 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL24095615 | 0.77 | ALDH1A1 (0.39) | P2RX3 | |
| SCHEMBL20652794 | 0.75 | P2RX3 (0.45) | P2RX3 | |
| SCHEMBL20655938 | 0.74 | ACHE (0.34) | P2RX3 | |
| SCHEMBL24095603 | 0.72 | FFAR4 (0.34) | P2RX3 | |
| SCHEMBL20652796 | 0.71 | P2RX3 (0.42) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652176-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2021-12-15 | — | — | EP | disclosed |
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |