Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4319665 | 0.81 | KMT2A (0.64) | ESRRGOPRM1OPRD1OPRK1LTB4R | |
| SCHEMBL3999705 | 0.76 | CDK8 (0.74) | CDK8CLK4KMT2ANPC1RAB9A | |
| SCHEMBL8758089 | 0.76 | ESRRG (0.56) | ESRRGCA2OPRM1OPRD1OPRK1 | |
| SCHEMBL154384 | 0.75 | CA2 (0.61) | CA2KMT2AESR1ESR2KDM4E | |
| SCHEMBL26294033 | 0.75 | ESRRG (0.49) | ESRRGCA2OPRM1OPRD1OPRK1 | |
| SCHEMBL4324200 | 0.74 | KMT2A (0.46) | ESRRGOPRM1OPRD1OPRK1CDK8 | |
| SCHEMBL23732700 | 0.74 | TMEM97 (0.54) | ESRRGOPRM1OPRD1OPRK1CDK8 | |
| SCHEMBL934532 | 0.74 | CA2 (0.59) | CA2KMT2AESR1ESR2KDM4E | |
| Butane SCHEMBL10453910 | 0.73 | CA2 (0.53) | CA2KMT2AESR1ESR2KDM4E | |
| SCHEMBL4938894 | 0.72 | ACHE (0.57) | CA2LTB4RKMT2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252640-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES, INC. (US) | 2021-12-16 | — | — | WO | disclosed |