SCHEMBL240967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL241248	0.88	ALDH1A1 (0.40)	OPRM1DRD4GRIN2DGRIN3BCHRM2
	SCHEMBL242123	0.81	OPRD1 (0.60)	OPRM1KCNH2ALDH1A1MEN1KMT2A
	SCHEMBL237991	0.78	MAPT (0.66)	CYP2D6ALDH1A1LMNAMAPTMAPK1
	SCHEMBL239854	0.78	MAPT (0.33)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL240699	0.78	PDE9A (0.35)	CYP2D6ALDH1A1LMNAMAPTMAPK1
	SCHEMBL239677	0.76	MAPT (0.33)	KCNH2ALDH1A1LMNAMAPTMAPK1
	SCHEMBL239103	0.75	ALDH1A1 (0.45)	ALDH1A1LMNAMAPTMAPK1GFER
	SCHEMBL241275	0.75	ALDH1A1 (0.33)	CYP2D6ALDH1A1LMNAMAPTMAPK1
	SCHEMBL239925	0.73	CYP11B1 (0.34)	CYP2D6ALDH1A1LMNAMAPTMAPK1
	SCHEMBL236849	0.73	DHFR (0.46)	GRIN2BCYP2D6ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.