Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | POLR1A | O95602 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096735 | 0.87 | BTK (0.46) | USP30BTKADORA1CNR1CNR2 | |
| SCHEMBL24096739 | 0.87 | BTK (0.46) | USP30BTKADORA1CNR1CNR2 | |
| SCHEMBL24096795 | 0.86 | USP30 (0.42) | POLBUSP30BTKADORA1CNR1 | |
| SCHEMBL24096729 | 0.80 | PIM1 (0.38) | POLR1AMAPK8USP30CNR1CNR2 | |
| SCHEMBL24096727 | 0.80 | PIM1 (0.38) | POLR1AMAPK8USP30CNR1CNR2 | |
| SCHEMBL24096768 | 0.80 | CTSL (0.33) | MAPK8 | |
| SCHEMBL24096772 | 0.80 | CTSL (0.33) | MAPK8 | |
| SCHEMBL24096644 | 0.78 | NTRK1 (0.35) | JAK3POLBMAPK8USP30BTK | |
| SCHEMBL24096869 | 0.74 | HDAC4 (0.46) | USP30BTKADORA1FPR3FPR2 | |
| SCHEMBL24096868 | 0.73 | POLB (0.36) | POLBGRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |