Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096739 | 1.00 | BTK (0.46) | BTKUSP30ADORA1PIK3CDCNR1 | |
| SCHEMBL24096795 | 0.95 | USP30 (0.42) | BTKUSP30ADORA1PIK3CDCNR1 | |
| SCHEMBL24096927 | 0.87 | JAK3 (0.36) | BTKUSP30ADORA1CNR1CNR2 | |
| SCHEMBL24096869 | 0.82 | HDAC4 (0.46) | BTKUSP30ADORA1PIK3CDHDAC4 | |
| SCHEMBL24096892 | 0.82 | HDAC4 (0.46) | BTKUSP30ADORA1PIK3CDHDAC4 | |
| SCHEMBL24096644 | 0.81 | NTRK1 (0.35) | BTKUSP30CNR1CNR2NPC1 | |
| SCHEMBL24096807 | 0.79 | BTK (0.40) | BTKUSP30ADORA1PIK3CDCNR1 | |
| SCHEMBL24096772 | 0.78 | CTSL (0.33) | — | |
| SCHEMBL2331346 | 0.77 | IGF1R (0.48) | BTKUSP30ADORA1PIK3CDCNR1 | |
| SCHEMBL31664319 | 0.77 | IGF1R (0.48) | BTKUSP30ADORA1PIK3CDCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |