Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096768 | 1.00 | CTSL (0.33) | CTSLCTSBCTSSCTSKP2RX3 | |
| SCHEMBL24096774 | 0.82 | L3MBTL1 (0.38) | P2RX3MAPK8SRCMAST3 | |
| SCHEMBL24096785 | 0.82 | L3MBTL1 (0.38) | P2RX3MAPK8SRCMAST3 | |
| SCHEMBL24096927 | 0.80 | JAK3 (0.36) | MAPK8 | |
| SCHEMBL24096739 | 0.78 | BTK (0.46) | — | |
| SCHEMBL24096735 | 0.78 | BTK (0.46) | — | |
| SCHEMBL24096644 | 0.78 | NTRK1 (0.35) | MAPK8HCRTR1HCRTR2 | |
| SCHEMBL24096795 | 0.76 | USP30 (0.42) | — | |
| SCHEMBL16350378 | 0.76 | NOS2 (0.39) | MEN1KMT2ANOS2SRC | |
| SCHEMBL24096850 | 0.70 | PIM1 (0.36) | MEN1KMT2AMAPK8HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |