Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | KAT7 | O95251 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 2/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414431 | 0.88 | HTR6 (0.39) | HTR6STAT3COMTFFAR4EDNRB | |
| SCHEMBL2409045 | 0.86 | HTR2C (0.36) | HTR2CSLC6A4HTR2ACOMTSSTR4 | |
| SCHEMBL2407101 | 0.85 | HTR2C (0.36) | HTR2CSLC6A4HTR2ACOMTAAK1 | |
| SCHEMBL1834426 | 0.83 | HTR2C (0.33) | HTR2CSLC6A4HTR2ASSTR4EDNRB | |
| SCHEMBL2410515 | 0.83 | HTR2C (0.33) | HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL2414689 | 0.83 | RIPK1 (0.35) | HTR2CSLC6A4HTR2AHTR6SSTR4 | |
| SCHEMBL2412160 | 0.82 | HTR2C (0.33) | HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL1832615 | 0.82 | TACR1 (0.33) | HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL2409441 | 0.82 | HTR2C (0.35) | HTR2CSLC6A4HTR2AHTR6SSTR4 | |
| SCHEMBL2409732 | 0.82 | HTR6 (0.34) | HTR6COMTFFAR4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |