Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4424124 | 0.94 | KAT6A (0.34) | HTR2CSLC6A4KAT6AKAT5HTR2A | |
| SCHEMBL1833792 | 0.90 | KAT6A (0.32) | HTR2CSLC6A4KAT6AKAT5HTR2A | |
| SCHEMBL2411207 | 0.90 | HTR6 (0.39) | HTR2CSLC6A4KAT6AKAT5MMP2 | |
| SCHEMBL2411042 | 0.89 | HTR6 (0.33) | HTR2CSLC6A4KAT6AKAT5HTR2A | |
| SCHEMBL4420269 | 0.88 | HTR6 (0.37) | HTR2CSLC6A4HTR2AKAT8HTR6 | |
| SCHEMBL1834426 | 0.88 | HTR2C (0.33) | HTR2CSLC6A4KAT6AKAT5HTR2A | |
| SCHEMBL4570001 | 0.88 | OXTR (0.34) | HTR2CSLC6A4KAT6AKAT5MMP2 | |
| SCHEMBL2412512 | 0.87 | HTR2C (0.31) | HTR2CSLC6A4KAT6AKAT5HTR2A | |
| SCHEMBL2408895 | 0.87 | SSTR4 (0.32) | HTR2CSLC6A4KAT6AKAT5HTR2A | |
| SCHEMBL2407588 | 0.87 | MET (0.38) | HTR2CSLC6A4KAT6AKAT5HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |