Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | NOS1 | P29475 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695006 | 0.96 | MAPT (0.68) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL1757487 | 0.91 | HIF1A (0.63) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL1134085 | 0.91 | HIF1A (0.76) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL30373777 | 0.91 | HIF1A (0.76) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL10055018 | 0.91 | NOS1 (0.63) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL27892973 | 0.89 | MAOB (0.57) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL25547611 | 0.89 | MAPT (0.60) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL631899 | 0.89 | MAPT (0.71) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL30480895 | 0.88 | MAPT (0.64) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL14689659 | 0.88 | MAPT (0.64) | MAPTALDH1A1KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685801-B2 | Derivatizable monomers and polymers, and methods for making and using same | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-06-27 | — | — | US | disclosed |
| US-11685801-B2 | Derivatizable monomers and polymers, and methods for making and using same | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-06-27 | — | — | US | disclosed |
| WO-2023083895-A1 | HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES AND METAL-FREE CLICK REACTIONS WITH THESE HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-05-19 | — | — | WO | disclosed |
| US-20210388138-A1 | DERIVATIZABLE MONOMERS AND POLYMERS, AND METHODS FOR MAKING AND USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2021-12-16 | — | — | US | disclosed |