Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | NOS1 | P29475 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24097464 | 0.96 | MAPT (0.68) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1134085 | 0.91 | HIF1A (0.76) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30373777 | 0.91 | HIF1A (0.76) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6693492 | 0.91 | MAPT (0.69) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL25547611 | 0.89 | MAPT (0.60) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL631899 | 0.89 | MAPT (0.71) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1757487 | 0.88 | HIF1A (0.63) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10055018 | 0.87 | NOS1 (0.63) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL21035304 | 0.85 | MAPT (0.64) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27892973 | 0.85 | MAOB (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | PAH, PNMT, OPRM1 | MAPT 3951/4885ALDH1A1 458/4885KDM4E 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.