Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NOS1 | P29475 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.55 |
| ▸ | CASR | P41180 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055018 | 0.93 | NOS1 (0.63) | HIF1APOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL24097464 | 0.91 | MAPT (0.68) | HIF1AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL30480895 | 0.90 | MAPT (0.64) | HIF1AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL1134085 | 0.90 | HIF1A (0.76) | HIF1AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL14689659 | 0.90 | MAPT (0.64) | HIF1AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL30373777 | 0.90 | HIF1A (0.76) | HIF1AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL6695006 | 0.88 | MAPT (0.68) | HIF1AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL17605113 | 0.87 | MEN1 (0.64) | MAPTGAAMEN1KMT2ANOS1 | |
| SCHEMBL9595678 | 0.86 | CHRM2 (0.56) | HIF1APOLBUSP2KDM4EALDH1A1 | |
| SCHEMBL2320797 | 0.86 | HIF1A (0.57) | HIF1APOLBMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326715-B1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | CE PHARM CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| CN-110305025-A | A method of benzylamine compound is synthesized by imines catalytic hydrogenation | 衢州学院 | 2019-10-08 | — | — | CN | disclosed |
| US-20180207628-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-07-26 | — | — | US | disclosed |
| US-20180207628-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-07-26 | — | — | US | disclosed |
| EP-3326715-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2018-05-30 | — | — | EP | disclosed |
| EP-1885718-B1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | LIFE TECHNOLOGIES CORP (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-1390340-B1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9366676-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150316558-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | MOLECULAR PROBES, INC. | 2015-11-05 | — | — | US | disclosed |
| EP-1973868-B1 | Novel elatonin ligands having antidepressant activity as well as sleep inducing properties | UNIV MCGILL (CA) | 2015-09-09 | — | — | EP | disclosed |
| US-20020013352-A1 | For therapy of gastrointestinal reflux disorders, eating disorders leading to obesity and irritable bowel disorder | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-01-31 | — | — | US | disclosed |
| EP-0802173-B1 | Process for producing heterocylic aromatic amine or arylamine | TOSOH CORP (JP) | 2001-12-19 | — | — | EP | disclosed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | disclosed |
| US-5929281-A | REACTING A HETROCYCLIC AROMATIC HALIDE WITH AN AMINE COMPOUND IN PRESENCE OF A BASE USING A TRI-TERT-BUTYLPHOSPHINE AND PALLADIUM COMPOUND CATALYST TO FORM HETEROCYCLIC AROMATIC AMINE COMPOUNDS | TOSOH CORPORATION (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0802173-A1 | Process for producing heterocylic aromatic amine or arylamine | Tosoh Corporation (JP) | 1997-10-22 | — | — | EP | disclosed |
| US-4758563-A | 3-alkoxy-2-aminopropyamines, cardiovascular compositions and use | MCNEILAB, INC. (US) | 1988-07-19 | — | — | US | disclosed |
| US-4727072-A | HYPOTENSIVE AGENTS | MCNEILAB, INC. (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0237191-A1 | 3-alkoxy-2-aminopropylamines useful as cardiovascular agents | McNeilab, Inc. (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4172944-A | Water insoluble styryl dyestuffs having hetero-aryl methylene substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-10-30 | — | — | US | disclosed |
| US-4046771-A | GREENISH-YELLOW SHADES ON SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013352-A1 | For therapy of gastrointestinal reflux disorders, eating disorders leading to obesity and irritable bowel disorder | MLNR, GIPR, NPY1R | HIF1A 3543/4885POLB 4511/4885MAPT 3521/4885 |
| US-20180207628-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | AOC2, AOC1, AOC3 | HIF1A 2449/4885POLB 2211/4885MAPT 1200/4885 |
| US-20150316558-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | POLRMT, DNA2, NSUN2 | HIF1A 2365/4885POLB 24/4885MAPT 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.