Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9887633 | 1.00 | SIGMAR1 (0.41) | SIGMAR1PIK3CDCYP1A2TDP1DRD3 | |
| SCHEMBL14707961 | 1.00 | SIGMAR1 (0.41) | SIGMAR1PIK3CDCYP1A2TDP1DRD3 | |
| SCHEMBL14980975 | 0.89 | L3MBTL1 (0.34) | SIGMAR1CYP1A2HRH3ALDH1A1 | |
| SCHEMBL9887646 | 0.89 | L3MBTL1 (0.34) | SIGMAR1CYP1A2HRH3ALDH1A1 | |
| SCHEMBL9887647 | 0.89 | L3MBTL1 (0.34) | SIGMAR1CYP1A2HRH3ALDH1A1 | |
| SCHEMBL21974892 | 0.88 | L3MBTL1 (0.37) | SIGMAR1CYP1A2HRH3ALDH1A1 | |
| SCHEMBL23020573 | 0.88 | L3MBTL1 (0.37) | SIGMAR1CYP1A2HRH3ALDH1A1 | |
| SCHEMBL12900872 | 0.86 | POLB (0.39) | SIGMAR1KDM4E | |
| SCHEMBL12900873 | 0.86 | POLB (0.39) | SIGMAR1KDM4E | |
| SCHEMBL23955948 | 0.84 | SIGMAR1 (0.36) | SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922267-A1 | PEGYLATED RECOMBINANT HUMAN GROWTH HORMONE COMPOUNDS | ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S (DK) | 2021-12-15 | — | — | EP | disclosed |