Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9887647 | 1.00 | L3MBTL1 (0.34) | L3MBTL1HRH3NPC1LMNAMAPK1 | |
| SCHEMBL14980975 | 1.00 | L3MBTL1 (0.34) | L3MBTL1HRH3NPC1LMNAMAPK1 | |
| SCHEMBL21974892 | 0.99 | L3MBTL1 (0.37) | L3MBTL1HRH3NPC1LMNAMAPK1 | |
| SCHEMBL23020573 | 0.99 | L3MBTL1 (0.37) | L3MBTL1HRH3NPC1LMNAMAPK1 | |
| SCHEMBL20879992 | 0.90 | CYP1A2 (0.37) | L3MBTL1HRH3NPC1MAPK1TP53 | |
| SCHEMBL12900874 | 0.90 | CYP1A2 (0.37) | L3MBTL1HRH3NPC1MAPK1TP53 | |
| SCHEMBL23955947 | 0.89 | SIGMAR1 (0.36) | CHRM5CHRM3MAPTALDH1A1SIGMAR1 | |
| SCHEMBL20879964 | 0.89 | KMT2A (0.38) | TP53MAPTALDH1A1 | |
| SCHEMBL23955948 | 0.89 | SIGMAR1 (0.36) | CHRM5CHRM3MAPTALDH1A1SIGMAR1 | |
| SCHEMBL24098133 | 0.89 | SIGMAR1 (0.41) | HRH3CYP1A2ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3050576-B1 | PEGYLATED RECOMBINANT HUMAN GROWTH HORMONE COMPOUNDS | ASCENDIS PHARMA ENDOCRINOLOGY DIV A/S (DK) | 2021-03-31 | — | — | EP | disclosed |
| EP-2237799-B1 | PRODRUG COMPRISING A SELF-CLEAVABLE LINKER | ASCENDIS PHARMA AS (DK) | 2019-04-10 | — | — | EP | disclosed |
| EP-2512450-B1 | DRY GROWTH HORMONE COMPOSITION TRANSIENTLY LINKED TO A POLYMER CARRIER | ASCENDIS PHARMA ENDOCRINOLOGY DIV A/S (DK) | 2018-02-07 | — | — | EP | disclosed |
| WO-2013053856-A1 | PREVENTION AND TREATMENT OF OCULAR CONDITIONS | ASCENDIS PHARMA A/S (DK) | 2013-04-18 | — | — | WO | disclosed |
| WO-2013024048-A1 | POLYMERIC HYPERBRANCHED CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2013-02-21 | — | — | WO | disclosed |
| WO-2013024047-A1 | HIGH-LOADING WATER-SOLUBLE CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2013-02-21 | — | — | WO | disclosed |
| WO-2013024049-A1 | PROTEIN CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2013-02-21 | — | — | WO | disclosed |
| WO-2011073234-A9 | DRY GROWTH HORMONE COMPOSITION TRANSIENTLY LINKED TO A POLYMER CARRIER | ASCENDIS PHARMA AS (DK) | 2012-06-07 | — | — | WO | disclosed |
| WO-2011073234-A2 | GROWTH HORMONE COMPOSITION | ASCENDIS PHARMA AS (DK) | 2011-06-23 | — | — | WO | disclosed |
| WO-2010100220-A1 | INTERFERON ALPHA CARRIER PRODRUGS | ASCENDIS PHARMA AS (DK) | 2010-09-10 | — | — | WO | disclosed |
| WO-2009133137-A2 | PEGYLATED RECOMBINANT HUMAN GROWTH HORMONE COMPOUNDS | ASCENDIS PHARMA AS (DK) | 2009-11-05 | — | — | WO | disclosed |
| WO-2009095479-A2 | PRODRUG COMPRISING A SELF-CLEAVABLE LINKER | ASCENDIS PHARMA AS (DK) | 2009-08-06 | — | — | WO | disclosed |