Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21974892 | 1.00 | L3MBTL1 (0.37) | L3MBTL1HRH3NPC1LMNAMAPK1 | |
| SCHEMBL9887647 | 0.99 | L3MBTL1 (0.34) | L3MBTL1HRH3NPC1LMNAMAPK1 | |
| SCHEMBL9887646 | 0.99 | L3MBTL1 (0.34) | L3MBTL1HRH3NPC1LMNAMAPK1 | |
| SCHEMBL14980975 | 0.99 | L3MBTL1 (0.34) | L3MBTL1HRH3NPC1LMNAMAPK1 | |
| SCHEMBL20879992 | 0.92 | CYP1A2 (0.37) | L3MBTL1HRH3NPC1MAPK1MAPT | |
| SCHEMBL12900874 | 0.92 | CYP1A2 (0.37) | L3MBTL1HRH3NPC1MAPK1MAPT | |
| SCHEMBL23955947 | 0.88 | SIGMAR1 (0.36) | MAPTALDH1A1CHRM5CHRM3SIGMAR1 | |
| SCHEMBL20879964 | 0.88 | KMT2A (0.38) | MAPTALDH1A1TP53 | |
| SCHEMBL23955948 | 0.88 | SIGMAR1 (0.36) | MAPTALDH1A1CHRM5CHRM3SIGMAR1 | |
| SCHEMBL24098133 | 0.88 | SIGMAR1 (0.41) | HRH3ALDH1A1CYP1A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782649-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | Ascendis Pharma A/S (DK) | 2021-02-24 | — | — | EP | disclosed |