Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26781563 | 1.00 | HPGDS (0.36) | HPGDSNPSR1DPP4L3MBTL1CNR2 | |
| SCHEMBL30471231 | 0.81 | CA2 (0.36) | HPGDSCNR2POLBCNR1ALDH1A1 | |
| SCHEMBL12462689 | 0.80 | NPSR1 (0.34) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL22600649 | 0.80 | L3MBTL1 (0.37) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL24263338 | 0.80 | L3MBTL1 (0.37) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL9805189 | 0.80 | ALDH1A1 (0.43) | NPSR1POLBMAPK1GAAALDH1A1 | |
| SCHEMBL12965977 | 0.80 | NPSR1 (0.34) | NPSR1L3MBTL1CNR2POLBMAPK1 | |
| SCHEMBL9341542 | 0.80 | ALDH1A1 (0.43) | NPSR1POLBMAPK1GAAALDH1A1 | |
| SCHEMBL23894830 | 0.77 | NPSR1 (0.35) | NPSR1DPP4L3MBTL1CNR2POLB | |
| SCHEMBL21638029 | 0.77 | NPSR1 (0.35) | NPSR1DPP4L3MBTL1CNR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021250531-A1 | 4-(4,5-DIHYDRO-1H-PYRAZOL-1-YL)PYRIMIDINE COMPOUND AS CANNABINOID RECEPTOR (CB1 RECEPTOR) ANTAGONISTS AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | 주식회사 종근당 | 2021-12-16 | — | — | WO | disclosed |