Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008300 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRRAB9ASLC9A1KMT2A | |
| SCHEMBL16382048 | 0.69 | IDO1 (0.43) | SMN1; SMN2TSHRRAB9ASLC9A1KMT2A | |
| SCHEMBL14685487 | 0.68 | RAB9A (0.45) | SMN1; SMN2TSHRRAB9ASLC9A1KMT2A | |
| SCHEMBL25583358 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRRAB9ASLC9A1KMT2A | |
| SCHEMBL19733923 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRRAB9ASLC9A1KEAP1 | |
| SCHEMBL13604186 | 0.67 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRRAB9ASLC9A1KMT2A | |
| SCHEMBL24081163 | 0.67 | SLC9A1 (0.44) | SMN1; SMN2TSHRRAB9ASLC9A1KMT2A | |
| SCHEMBL20938974 | 0.67 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRRAB9ASLC9A1KMT2A | |
| SCHEMBL12204569 | 0.67 | RAB9A (0.56) | SMN1; SMN2TSHRRAB9ASLC9A1KMT2A | |
| SCHEMBL29317012 | 0.66 | KCNMA1 (0.50) | SMN1; SMN2TSHRRAB9ASLC9A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922247-A1 | 15-PGDH INHIBITOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-15 | — | — | EP | disclosed |