Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.73 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.73 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.65 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24101112 | 0.96 | ALDH1A1 (0.71) | HTTALDH1A1KMT2AMEN1S1PR4 | |
| SCHEMBL25994858 | 0.93 | ALDH1A1 (0.67) | HTTALDH1A1KMT2AMEN1S1PR4 | |
| SCHEMBL24100990 | 0.91 | ALDH1A1 (0.64) | HTTALDH1A1KMT2AMEN1S1PR4 | |
| SCHEMBL24100858 | 0.90 | ALDH1A1 (0.76) | HTTALDH1A1KMT2AMEN1S1PR4 | |
| SCHEMBL25352892 | 0.90 | HTT (0.72) | HTTALDH1A1KMT2AMEN1S1PR4 | |
| SCHEMBL13802907 | 0.90 | ALDH1A1 (0.79) | HTTALDH1A1KMT2AMEN1S1PR4 | |
| SCHEMBL24100407 | 0.88 | KMT2A (0.88) | HTTALDH1A1KMT2AMEN1S1PR4 | |
| SCHEMBL24100884 | 0.88 | KMT2A (0.72) | HTTALDH1A1KMT2AMEN1S1PR4 | |
| SCHEMBL24100943 | 0.88 | HTT (0.65) | HTTALDH1A1KMT2AMEN1S1PR4 | |
| SCHEMBL24101317 | 0.87 | KMT2A (0.71) | HTTALDH1A1KMT2AMEN1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233533-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | HEALTH RESEARCH, INC. (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230233533-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | HEALTH RESEARCH, INC. (US) | 2023-07-27 | — | — | US | disclosed |
| WO-2021252068-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | HEALTH RESEARCH, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233533-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | PRPF8, PRPF40A, PRPF19 | HTT 3823/4885ALDH1A1 3731/4885KMT2A 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.