Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.44 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.44 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24101404 | 0.77 | CCNK (0.52) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL24101952 | 0.75 | MEN1 (0.52) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL24101693 | 0.75 | CCNK (0.70) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL24101409 | 0.74 | TDP1 (0.65) | ALDH1A1MEN1KMT2APOLBESR2 | |
| SCHEMBL24101951 | 0.70 | LMNA (0.57) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL22639923 | 0.67 | PDE5A (0.55) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL24101942 | 0.66 | PDE5A (0.51) | KDM4EMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL5251770 | 0.65 | NPC1 (0.62) | ALDH1A1POLBNPC1RAB9AMAPT | |
| SCHEMBL10932130 | 0.65 | HPGD (0.64) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL24358078 | 0.64 | KCNN1 (0.76) | ALDH1A1KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249517-A1 | A MOLECULAR GLUE REGULATING CDK12-DDB1 INTERACTION TO TRIGGER CYCLIN K DEGRADATION | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-12-16 | — | — | WO | disclosed |