Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC12A2 | P55011 | 1/20 | 0.51 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24101706 | 0.85 | CCNK (0.64) | SLC12A2SLC12A5MEN1KMT2AALDH1A1 | |
| SCHEMBL24101789 | 0.83 | MEN1 (0.54) | SLC12A2SLC12A5MEN1KMT2AALDH1A1 | |
| SCHEMBL24101694 | 0.81 | MEN1 (0.57) | SLC12A2SLC12A5MEN1KMT2AALDH1A1 | |
| SCHEMBL24101793 | 0.80 | RAB9A (0.53) | SLC12A2SLC12A5MEN1KMT2AALDH1A1 | |
| SCHEMBL24101416 | 0.77 | GAA (0.66) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL24101410 | 0.77 | MEN1 (0.61) | SLC12A2SLC12A5MEN1KMT2AALDH1A1 | |
| SCHEMBL24101448 | 0.76 | ALDH1A1 (0.60) | SLC12A2SLC12A5MEN1KMT2AALDH1A1 | |
| SCHEMBL24101798 | 0.76 | L3MBTL1 (0.56) | SLC12A2SLC12A5MEN1KMT2AALDH1A1 | |
| SCHEMBL24101791 | 0.73 | LMNA (0.56) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL24101796 | 0.71 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249517-A1 | A MOLECULAR GLUE REGULATING CDK12-DDB1 INTERACTION TO TRIGGER CYCLIN K DEGRADATION | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-12-16 | — | — | WO | disclosed |