Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 16/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24102463 | 0.80 | FFAR2 (0.55) | FFAR2 | |
| SCHEMBL24102467 | 0.80 | FFAR2 (0.55) | FFAR2 | |
| SCHEMBL21637895 | 0.78 | NOTUM (0.44) | FFAR2MAOB | |
| SCHEMBL23658508 | 0.74 | FFAR2 (0.78) | FFAR2 | |
| SCHEMBL10631611 | 0.73 | HSP90AA1 (0.60) | MAOAMAOBRIPK1EGFR | |
| SCHEMBL1513502 | 0.72 | KDM4E (0.56) | — | |
| SCHEMBL25369062 | 0.70 | FFAR2 (0.59) | FFAR2 | |
| SCHEMBL2042521 | 0.69 | FFAR2 (0.57) | FFAR2 | |
| SCHEMBL2038056 | 0.68 | FFAR2 (0.71) | FFAR2 | |
| SCHEMBL29787531 | 0.68 | FFAR2 (0.71) | FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271921-A1 | SYNTHESIS OF (2S,5R)-5-(2-CHLOROPHENYL)-1-(2'-METHOXY-[1,1'-BIPHENYL]-4- CARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID | EPICS THERAPEUTICS (BE) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271921-A1 | SYNTHESIS OF (2S,5R)-5-(2-CHLOROPHENYL)-1-(2'-METHOXY-[1,1'-BIPHENYL]-4- CARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID | IL1A, IL1B, IL6 | FFAR2 1023/4885MAOA 3102/4885MAOB 2665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.