Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830980 | 0.88 | NAPRT (0.33) | — | |
| SCHEMBL5006157 | 0.86 | PLCG1 (0.34) | PLCG1SLC22A12 | |
| SCHEMBL2416412 | 0.85 | DHODH (0.32) | — | |
| SCHEMBL2408759 | 0.84 | DHODH (0.33) | — | |
| SCHEMBL2410739 | 0.80 | PLCG1 (0.37) | PLCG1 | |
| SCHEMBL2411262 | 0.79 | PLCG1 (0.35) | PLCG1CTSKSLC22A12 | |
| SCHEMBL2410603 | 0.76 | HTR6 (0.33) | PLCG1CTSK | |
| SCHEMBL2410565 | 0.76 | PLCG1 (0.36) | PLCG1CTSK | |
| SCHEMBL5006162 | 0.74 | MTNR1A (0.41) | PLCG1 | |
| SCHEMBL2408012 | 0.73 | PTGDR2 (0.31) | PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |