Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410603 | 0.94 | HTR6 (0.33) | PTGDR2PLCG1HTR6 | |
| SCHEMBL2411045 | 0.90 | PTGER2 (0.33) | PTGDR2PTGER2HTR6RORCCHRNB2 | |
| SCHEMBL2409876 | 0.90 | HTR6 (0.34) | PTGDR2PTGER2PLCG1HTR6 | |
| SCHEMBL2412057 | 0.89 | PPME1 (0.34) | PTGDR2HTR6RORC | |
| SCHEMBL2408863 | 0.88 | GPBAR1 (0.33) | PTGDR2PTGER2HTR6RORC | |
| SCHEMBL4998756 | 0.88 | HTR6 (0.34) | PTGDR2HTR6CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2408646 | 0.87 | RORC (0.33) | PTGDR2PTGER2HTR6RORC | |
| SCHEMBL2409899 | 0.87 | MET (0.38) | PTGDR2PLCG1HTR6 | |
| SCHEMBL2408006 | 0.84 | PLCG1 (0.32) | PLCG1HTR6 | |
| SCHEMBL2410118 | 0.83 | PPME1 (0.35) | PTGDR2HTR6RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |