Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.57 |
| ▸ | ITGAL | P20701 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536009 | 1.00 | ITGB2 (0.57) | ITGB2ICAM1ITGALCA1CA2 | |
| Hydrochloric Acid SCHEMBL28591529 | 0.99 | ITGB2 (0.56) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL28274103 | 0.87 | ITGB2 (0.58) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL29160709 | 0.86 | CYP3A4 (0.50) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL4535076 | 0.85 | HTR1D (0.48) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL19951587 | 0.84 | ITGB2 (0.51) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL27413426 | 0.84 | ITGB2 (0.67) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL29222912 | 0.83 | ITGB2 (0.46) | ITGB2ICAM1ITGALSLC6A5CYP3A4 | |
| SCHEMBL6026427 | 0.81 | ITGB2 (0.64) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL14952736 | 0.81 | ITGB2 (0.61) | ITGB2ICAM1ITGALCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210388142-A1 | AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM | JOHNSON & JOHNSON VISION CARE, INC. | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210388142-A1 | AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM | ARGLU1, BCAT2, BCAT1 | ITGB2 1257/4885ICAM1 1020/4885ITGAL 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.