Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22833179 | 0.83 | LMNA (0.48) | LMNASMN1; SMN2PRSS1TPSAB1L3MBTL1 | |
| SCHEMBL24110551 | 0.81 | PRSS1 (0.46) | LMNASMN1; SMN2PRSS1TPSAB1L3MBTL1 | |
| SCHEMBL25306765 | 0.81 | ALDH1A1 (0.43) | LMNASMN1; SMN2PRSS1TPSAB1L3MBTL1 | |
| SCHEMBL20467627 | 0.81 | HTT (0.53) | LMNASMN1; SMN2PRSS1TPSAB1L3MBTL1 | |
| SCHEMBL13572586 | 0.80 | TPSAB1 (0.39) | LMNASMN1; SMN2PRSS1TPSAB1L3MBTL1 | |
| SCHEMBL25303252 | 0.78 | PLAU (0.49) | LMNASMN1; SMN2PRSS1TPSAB1L3MBTL1 | |
| SCHEMBL17072452 | 0.78 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2PRSS1TPSAB1L3MBTL1 | |
| SCHEMBL30169875 | 0.78 | MEN1 (0.41) | LMNASMN1; SMN2PRSS1L3MBTL1MAPT | |
| SCHEMBL16574772 | 0.77 | ALB (0.44) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL16574796 | 0.76 | ANPEP (0.45) | LMNASMN1; SMN2PRSS1TPSAB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252708-A1 | STABILIZED TRIOXACARCIN ANTIBODY DRUG CONJUGATES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-12-16 | — | — | WO | disclosed |