Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17151094 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL24835698 | 0.83 | ALDH1A1 (0.45) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL17232558 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL17448403 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL19154486 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL22154185 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL18430370 | 0.79 | L3MBTL1 (0.45) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL19154445 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL24110552 | 0.78 | LMNA (0.43) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL23901065 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHTTL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | CD44, EPCAM, ABCG2 | SMN1; SMN2 4201/4885LMNA 1567/4885HTT 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.