Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103185 | 1.00 | ABCG2 (0.42) | ABCG2CSNK2A1ALOX12PIK3CDRAD52 | |
| SCHEMBL23958210 | 0.89 | GPR6 (0.41) | ABCG2CSNK2A1PIK3CDRAD52KMT2A | |
| SCHEMBL23931443 | 0.88 | PDE7A (0.43) | ABCG2CSNK2A1ALOX12KMT2A | |
| SCHEMBL30103276 | 0.88 | PDE7A (0.43) | ABCG2CSNK2A1ALOX12KMT2A | |
| SCHEMBL23958200 | 0.86 | PIK3CD (0.38) | PIK3CDPI4KAPIK3CGG6PD | |
| SCHEMBL30103172 | 0.86 | PIK3CD (0.38) | PIK3CDPI4KAPIK3CGG6PD | |
| SCHEMBL23958265 | 0.84 | PIK3CD (0.46) | ABCG2ALOX12PIK3CDRAD52KMT2A | |
| SCHEMBL24110981 | 0.84 | ALOX12 (0.43) | ABCG2ALOX12RAD52KMT2API4KA | |
| SCHEMBL23958278 | 0.84 | TUBB4A (0.45) | ALOX12RAD52KMT2A | |
| SCHEMBL23958121 | 0.84 | ALOX12 (0.43) | ALOX12RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387967-A1 | 2-HETEROARYL AMINOQUINAZOLINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387967-A1 | 2-HETEROARYL AMINOQUINAZOLINONE DERIVATIVE | CRKL, CLIC4, CLIC1 | ABCG2 191/4885CSNK2A1 70/4885ALOX12 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.