Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPD | P32754 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103275 | 0.85 | TDO2 (0.48) | PDE7AALDH1A1LMNAL3MBTL1PDE4D | |
| SCHEMBL23958208 | 0.85 | TDO2 (0.48) | PDE7AALDH1A1LMNAL3MBTL1PDE4D | |
| SCHEMBL30103276 | 0.83 | PDE7A (0.43) | PDE7AALDH1A1LMNAL3MBTL1HPD | |
| SCHEMBL23931443 | 0.83 | PDE7A (0.43) | PDE7AALDH1A1LMNAL3MBTL1HPD | |
| SCHEMBL23958346 | 0.79 | PDE7A (0.46) | PDE7AALDH1A1LMNAL3MBTL1JUN | |
| SCHEMBL24090141 | 0.79 | USP2 (0.43) | PDE4BALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL30103264 | 0.77 | MDM2 (0.49) | MAPTKMT2AALOX12KDM4ESMN1; SMN2 | |
| SCHEMBL23958215 | 0.77 | MDM2 (0.49) | MAPTKMT2AALOX12KDM4ESMN1; SMN2 | |
| SCHEMBL23958217 | 0.77 | MET (0.49) | LMNAMAPTALOX12 | |
| SCHEMBL23958205 | 0.76 | TDO2 (0.48) | L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387967-A1 | 2-HETEROARYL AMINOQUINAZOLINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387967-A1 | 2-HETEROARYL AMINOQUINAZOLINONE DERIVATIVE | CRKL, CLIC4, CLIC1 | PDE4B 2766/4885PDE7A 3371/4885ALDH1A1 1803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.