Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422173 | 0.90 | HTR6 (0.42) | HTR6KEAP1MMP8MMP3FFAR1 | |
| SCHEMBL2409441 | 0.90 | HTR2C (0.35) | HTR6MMP8HTR2CSLC6A4KAT6A | |
| SCHEMBL2408606 | 0.85 | TDP1 (0.37) | HTR2CSLC6A4 | |
| SCHEMBL2411210 | 0.85 | HTR6 (0.38) | HTR6KEAP1MMP8MMP3FFAR1 | |
| SCHEMBL4566561 | 0.85 | HTR6 (0.40) | HTR6KEAP1MMP8MMP3FFAR1 | |
| SCHEMBL1833792 | 0.85 | KAT6A (0.32) | MMP8HTR2CSLC6A4KAT6AKAT5 | |
| SCHEMBL2415887 | 0.84 | HTR2C (0.34) | HTR2CSLC6A4KAT6AKAT5 | |
| SCHEMBL2409035 | 0.84 | HTR2C (0.35) | HTR2CSLC6A4KAT6AKAT5 | |
| Hydrochloric Acid SCHEMBL4424124 | 0.84 | KAT6A (0.34) | HTR2CSLC6A4KAT6AKAT5 | |
| SCHEMBL2412417 | 0.84 | HTR2C (0.35) | HTR6HTR2CSLC6A4KAT6AKAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |