Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681899 | 0.78 | OPRM1 (0.39) | NOTUMNPC1RAB9APKMSIGMAR1 | |
| SCHEMBL2089551 | 0.78 | OPRM1 (0.39) | NOTUMNPC1RAB9APKMSIGMAR1 | |
| SCHEMBL12387928 | 0.78 | SIGMAR1 (0.36) | NOTUMADORA2ASIGMAR1RXFP1PARP1 | |
| SCHEMBL3898933 | 0.75 | ACE (0.46) | MEN1MAPTKMT2ATAAR1PREP | |
| SCHEMBL17559354 | 0.75 | ACE (0.46) | MEN1MAPTKMT2ATAAR1PREP | |
| SCHEMBL5243620 | 0.75 | ACE (0.46) | MEN1MAPTKMT2ATAAR1PREP | |
| SCHEMBL19473382 | 0.74 | ADORA2A (0.33) | NOTUMADORA2ASIGMAR1RXFP1PARP1 | |
| SCHEMBL19473353 | 0.74 | ADORA2A (0.33) | NOTUMADORA2ASIGMAR1RXFP1PARP1 | |
| SCHEMBL20342104 | 0.71 | NOTUM (0.47) | NOTUMNPC1RAB9ANAMPTPREP | |
| SCHEMBL26638792 | 0.71 | NOTUM (0.41) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925667-A1 | SELECTIVE TMPRSS2 INHIBITORS AND MEDICAL USE THEREOF | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-12-22 | — | — | EP | disclosed |