Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DUT | P33316 | 12/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24115281 | 0.86 | DUT (0.49) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL24115234 | 0.80 | PKM (0.50) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL5001166 | 0.78 | DUT (0.51) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL4311546 | 0.77 | DUT (0.50) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL5000786 | 0.77 | DUT (0.50) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL23873265 | 0.74 | PKM (0.60) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL7133033 | 0.74 | PKM (0.65) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL7136481 | 0.74 | PKM (0.56) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL11983580 | 0.73 | ALDH1A1 (0.58) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL14478216 | 0.71 | PKM (0.61) | PKMCRBNALDH1A1LMNADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925667-A1 | SELECTIVE TMPRSS2 INHIBITORS AND MEDICAL USE THEREOF | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-12-22 | — | — | EP | disclosed |