Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DUT | P33316 | 10/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472497 | 0.84 | PKM (0.55) | PKMALDH1A1LMNADUTL3MBTL1 | |
| SCHEMBL7140825 | 0.84 | PKM (0.55) | PKMALDH1A1LMNADUTL3MBTL1 | |
| SCHEMBL5180755 | 0.81 | PKM (0.53) | PKMALDH1A1LMNADUTL3MBTL1 | |
| SCHEMBL7133033 | 0.81 | PKM (0.65) | PKMALDH1A1LMNADUTL3MBTL1 | |
| SCHEMBL337057 | 0.79 | PKM (0.50) | PKMALDH1A1LMNADUTL3MBTL1 | |
| SCHEMBL14478216 | 0.78 | PKM (0.61) | PKMALDH1A1LMNADUTL3MBTL1 | |
| SCHEMBL667078 | 0.78 | PKM (0.61) | PKMALDH1A1LMNADUTL3MBTL1 | |
| SCHEMBL338055 | 0.78 | ALDH1A1 (0.56) | PKMALDH1A1LMNADUTL3MBTL1 | |
| Formic Acid SCHEMBL29998806 | 0.78 | PKM (0.53) | PKMALDH1A1LMNADUTL3MBTL1 | |
| (S)-Willardiine SCHEMBL438494 | 0.78 | GRIA1 (0.56) | PKMALDH1A1LMNADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230129710-A1 | Methods and Reagents for Synthesizing Nucleosides and Analogues Thereof | SIMON FRASER UNIVERSITY (CA) | 2023-04-27 | — | — | US | disclosed |
| US-20230129710-A1 | Methods and Reagents for Synthesizing Nucleosides and Analogues Thereof | SIMON FRASER UNIVERSITY (CA) | 2023-04-27 | — | — | US | disclosed |
| WO-2021191830-A1 | METHODS AND REAGENTS FOR SYNTHESIZING NUCLEOSIDES AND ANALOGUES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2021-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230129710-A1 | Methods and Reagents for Synthesizing Nucleosides and Analogues Thereof | NUDT1, ADAR, APRT | PKM 594/4885ALDH1A1 55/4885LMNA 1420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.