Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721539 | 0.83 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9721443 | 0.83 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL10230053 | 0.81 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL12393190 | 0.80 | CTSK (0.46) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL3138315 | 0.80 | CA14 (0.62) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL22688574 | 0.78 | CA14 (0.56) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL15254571 | 0.78 | CA14 (0.52) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL2579949 | 0.77 | CTSK (0.44) | CA14CTSKMAPTCHRM2CHRM4 | |
| SCHEMBL21761825 | 0.76 | CA3 (0.68) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL10230055 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395292-A1 | Detection Method for Natural and Modified Small Nucleic Acids | ZATA PHARMACEUTICALS, INC. | 2021-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395292-A1 | Detection Method for Natural and Modified Small Nucleic Acids | NCL, POLRMT, NSUN3 | ALDH1A1 4651/4885SMN1; SMN2 3008/4885POLB 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.