Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 6/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | F11 | P03951 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777173 | 1.00 | NPC1 (0.60) | NPC1RAB9AL3MBTL1CTSLCNR1 | |
| SCHEMBL22822798 | 0.92 | NPC1 (0.60) | NPC1RAB9ACTSLCNR1CNR2 | |
| SCHEMBL20777179 | 0.92 | L3MBTL1 (0.67) | L3MBTL1CTSLCNR1CNR2KMT2A | |
| SCHEMBL20777238 | 0.92 | L3MBTL1 (0.67) | L3MBTL1CTSLCNR1CNR2KMT2A | |
| SCHEMBL20777169 | 0.90 | CTSL (0.49) | NPC1RAB9AL3MBTL1CTSLCNR1 | |
| SCHEMBL20777225 | 0.88 | L3MBTL1 (0.53) | L3MBTL1CTSLCNR1CNR2KMT2A | |
| SCHEMBL22822797 | 0.88 | L3MBTL1 (0.53) | L3MBTL1CTSLCNR1CNR2KMT2A | |
| SCHEMBL20777178 | 0.86 | CTSL (0.52) | L3MBTL1CTSLCNR1CNR2KMT2A | |
| SCHEMBL20777212 | 0.86 | NPC1 (0.55) | NPC1RAB9AL3MBTL1CTSLKMT2A | |
| SCHEMBL20777199 | 0.86 | CTSL (0.52) | L3MBTL1CTSLCNR1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395203-A1 | DUAL ACTING FKBP12 AND FKBP52 INHIBITORS | PLEX PHARMACEUTICALS, INC. | 2021-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395203-A1 | DUAL ACTING FKBP12 AND FKBP52 INHIBITORS | FKBP2, FKBP1B, FKBP1A | NPC1 1443/4885RAB9A 1223/4885L3MBTL1 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.