Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124182 | 0.87 | KCNK3 (0.40) | KCNK3KMT2APOLBHTTSMN1; SMN2 | |
| SCHEMBL24124923 | 0.79 | KMT2A (0.51) | KCNK3KMT2APOLBHTTKCNK9 | |
| SCHEMBL24124178 | 0.77 | HDAC3 (0.54) | KCNK3KMT2APOLBMEN1HDAC3 | |
| SCHEMBL24124948 | 0.74 | HDAC1 (0.44) | KMT2APOLBALDH1A1LMNAMEN1 | |
| SCHEMBL24247784 | 0.72 | KMT2A (0.43) | KCNK3KMT2APOLBHTTSMN1; SMN2 | |
| SCHEMBL24124189 | 0.70 | HDAC8 (0.54) | KCNK3KMT2AKCNK9HDAC3HDAC1 | |
| SCHEMBL24124876 | 0.68 | GPR27 (0.67) | KMT2APOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL24124180 | 0.68 | NR1H4 (0.68) | KMT2APOLBSMN1; SMN2MAPK1LMNA | |
| SCHEMBL24124921 | 0.68 | KMT2A (0.50) | KCNK3KMT2ASMN1; SMN2LMNAKCNK9 | |
| SCHEMBL2969962 | 0.67 | MAPK14 (0.59) | KCNK3KMT2ASMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |