Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124174 | 0.87 | KCNK3 (0.45) | KCNK3KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL24124178 | 0.75 | HDAC3 (0.54) | KCNK3KMT2AMEN1POLBNR1H4 | |
| SCHEMBL24124923 | 0.74 | KMT2A (0.51) | KCNK3KMT2AMEN1HTTNPC1 | |
| SCHEMBL24124948 | 0.72 | HDAC1 (0.44) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL24124189 | 0.71 | HDAC8 (0.54) | KCNK3KMT2AKCNK9NR1H4 | |
| SCHEMBL24124180 | 0.68 | NR1H4 (0.68) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL24124921 | 0.68 | KMT2A (0.50) | KCNK3KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL24124876 | 0.66 | GPR27 (0.67) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6813579 | 0.66 | HDAC2 (0.56) | KCNK3KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL24124210 | 0.65 | HDAC3 (0.46) | KMT2AMEN1MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |