Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124183 | 0.85 | HDAC1 (0.63) | HDAC1HDAC3HDAC2NCOR2LMNA | |
| SCHEMBL25924692 | 0.79 | HDAC1 (0.66) | HDAC1HDAC3HDAC2NCOR2LMNA | |
| SCHEMBL25921604 | 0.74 | BAZ1A (0.54) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL24124938 | 0.72 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NCOR2LMNA | |
| SCHEMBL24124178 | 0.72 | HDAC3 (0.54) | HDAC1HDAC3HDAC2NCOR2NR1H4 | |
| SCHEMBL24124308 | 0.71 | TRPV1 (0.49) | HDAC1HDAC3HDAC2NCOR2LMNA | |
| SCHEMBL24124184 | 0.71 | HDAC1 (0.47) | HDAC1HDAC3HDAC2NCOR2LMNA | |
| SCHEMBL25933321 | 0.71 | HDAC1 (0.45) | HDAC1HDAC3HDAC2NCOR2LMNA | |
| SCHEMBL24125182 | 0.69 | ALDH1A1 (0.55) | HDAC1HDAC3HDAC2NCOR2LMNA | |
| SCHEMBL24125319 | 0.69 | RAB9A (0.60) | HDAC1HDAC3HDAC2NCOR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |