Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24125069 | 0.79 | SMYD3 (0.50) | ALDH1A1TSHRMAPTKMT2AMEN1 | |
| SCHEMBL24124808 | 0.74 | RAB9A (0.42) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24124997 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTKMT2ANPC1 | |
| SCHEMBL9826530 | 0.72 | BRD4 (0.49) | THRBALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL24124230 | 0.70 | HDAC1 (0.57) | ALDH1A1TP53MAPTKMT2AMEN1 | |
| SCHEMBL24125152 | 0.69 | RAB9A (0.55) | ALDH1A1TP53MAPTKMT2AMEN1 | |
| SCHEMBL24124283 | 0.69 | RAB9A (0.63) | ALDH1A1TP53MAPTKMT2ANPC1 | |
| SCHEMBL24124682 | 0.68 | RAB9A (0.48) | THRBTP53MAPTKMT2ANPC1 | |
| SCHEMBL24124203 | 0.67 | HDAC1 (0.49) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL24124323 | 0.67 | TRPV1 (0.50) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |